Highlights • Comparison of the effects of gait-training strategies for Parkinson's disease. • Robot-assisted gait training and treadmill training were randomly allocated. • Gait speed on the 10-m walk test did not vary between the groups. • Cognitive dual-task interference showed a training-related group difference. • The neural mechanisms of gait improvement differed by training strategy. Abstract Background Robot-assisted gait training (RAGT) may have beneficial effects on Parkinson's disease (PD); however, the evidence to date is inconsistent. Objectives This study compared the effects of RAGT and treadmill training (TT) on gait speed, dual-task gait performance, and changes in resting-state brain functional connectivity in individuals with PD. Methods In this prospective, single-center, randomized controlled trial with a parallel two-group design, 44 participants were randomly allocated to undergo 12 sessions (3 times per week for 4 weeks) of RAGT or TT. The primary outcome...
Walkbot is a state-of-the-art lower limb rehabilitation exoskeleton robot that provides natural walking movements and various training programs for patients with walking disorders due to stroke, spinal cord injury, cerebral palsy, etc